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Amitriptyline hydrochloride overdose

Definition

Amitriptyline hydrochloride is a type of prescription medicine called a tricyclic antidepressant. Amitriptyline hydrochloride overdose occurs when someone accidentally or intentionally takes more than the normal or recommended amount of this medication.

This is for information only and not for use in the treatment or management of an actual poison exposure. If you have an exposure, you should call your local emergency number (such as 911) or the National Poison Control Center at 1-800-222-1222.


Symptoms

  • Airways and lungs
    • Slowed, labored breathing
  • Bladder and kidneys
    • Urinary hesitancy
  • Eyes, ears, nose, and throat
    • Blurred vision
    • Dry mouth
    • Enlarged pupils
  • Heart and blood
    • Low blood pressure
    • Rapid heart rate
    • Shock
  • Nervous system
    • Agitation
    • Coma (sudden onset)
    • Convulsions (sudden onset)
    • Drowsiness
    • Dizziness
    • Hallucinations
    • Headache
    • Inability to concentrate
    • Muscle rigidity
    • Restlessness
    • Seizures
    • Stupor (lack of alertness)
    • Uncoordinated movement
  • Stomach and intestines
    • Constipation
    • Increased appetite
    • Weight gain
    • Vomiting

Prognosis

Amitriptyline hydrochloride can be an extremely serious overdose.

Patients who swallow an excessive amount of this drug are almost always admitted to hospital.

How well a patient does depends on how much of the drug was swallowed and how quickly treatment was received. The faster a patient gets medical help, the better the chance of recovery.